S100 Antibodies

S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an α and β chain whereas S100B is composed of two β chains. Antibody to S100 stains Schwannomas, ependymomas, astrogliomas, almost all benign and malignant melanomas and their metastases. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant protein encoding human S100 protein

Molecular Weight: 21-24kDa

Positive Control: Melanoma or Schwannoma

Cellular Localization: Cytoplasmic

Recommended for:

Immunohistochemistry (Formalin/paraffin)

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