Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).
Calcium and DAG-regulated guanine nucleotide exchange factor III; calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III; CalDAG-GEFIII; Guanine nucleotide exchange factor for Rap1; OTTHUMP00000201245 calcium and DAG-regulated guanine nucleotide exchange factor III guanine nucleotide exchange factor for Rap1 ras guanyl-releasing protein 3; RAS guanyl releasing protein 3 (calcium and DAG-regulated); Ras guanyl-releasing protein 3
Cat # 15976094
100 µL
Cat # 11524871
100 µL
Cat # 16801244
20 µL
Cat # 16858725
150 µL
Cat # 16891234
150 µL
Cat # 16589641
100 µL
Cat # 15966094
100 µL
Cat # 16155076
100 µL
Cat # 13442257
100 µL
Cat # 15916104
100 µL
Cat # 16868725
20 µL
Cat # 16692805
100 µL
Cat # 15978934
100 µL
Cat # 16145076
50 µg
Cat # 16045375
100 µg
Cat # 16135076
50 µL
Cat # 16165076
100 µg
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk To A Specialist NowIf an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.