The Ras-related low molecular mass GTPases participate in signal transduction involving a variety of cellular functions, including cell-cycle progression, cellular differentiation, cytoskeletal organization, protein transport and secretion. The Ras-GTPase-activating protein (RASGAP) forms a complex with a second protein, p190, in growth factor stimulated and tyrosinekinase transformed cells. The RASGAP p190 complex may serve to couple Ras- and Rho-mediated signaling pathways. RASGAP forms an abundant SH2-mediated complex with p190 RhoGAP in cells expressing activated tyrosine kinases.
CM-AVM CMAVM DKFZp434N071 GAP PKWS RASA RASGAP p120GAP p120RASGAP; GAP1m; GTPase-activating protein 1m; GTPase-activating protein of RAS; Ras GTPase-activating protein 2
Cat # 15795141
100 µL
Cat # 15684665
100 µL
Cat # 15785141
100 µL
Cat # 16185350
100 uL
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