Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia. Phosphorylation of Rb at S608 depends on CDK4.
gene trap PAT 12; Rab-3A-interacting protein; RAB3A-interacting protein; RAB3IP; rab3ip {ECO:0000250|UniProtKB:Q96QF0}; rabin 3; Rabin-3; SSX2 interacting protein; SSX2-interacting protein
Cat # 16559761
100 µL
Cat # 15586291
100 µg
Cat # 15536312
100 µL
Cat # 15526312
100 µL
Cat # 15926674
100 µL
Cat # 16135759
50 µg
Cat # 16643945
100 µL
Cat # 16526831
100 µL
Cat # 15916674
100 µL
Cat # 16320435
100 µL
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