Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
BRI3 BRICD2C Cerebral protein 14 E25 E25C integral membrane protein 2C ITM2C ITM3 PSEC0047 Transmembrane protein BRI3; BRICHOS domain containing 2C; Cerebral protein 14; CT-BRI3; Integral membrane protein 2C; integral membrane protein 3; Transmembrane protein BRI3
Cat # 16861894
20 µL
Cat # 13445347
100 µL
Cat # 16867065
150 µL
Cat # 16195183
50 ug
Cat # 15712794
25 ug
Cat # 16877065
20 µL
Cat # 16851894
150 µL
Cat # 13438974
100 ug
Cat # 17167488
400 µL
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