IR Antibodies

Insulin receptor (IR), belongs to the growth factor receptor tyrosine kinase superfamily which regulates multiple signaling pathways. It is a heterotetrameric membrane glycoprotein consisting of alpha and beta subunits encoded by the INSR gene in humans. IR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in IR. In humans, the IR gene is located on chromosome 19.

701049 detects IR in Human samples. 701049 has been successfully used in WB procedures. The immunogen for 701049 is recombinant protein corresponding to amino acids 1283-1382 of human insulin receptor.

Applications:

Western Blotting

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