IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5′ UTRs.
IARS IARS1 IleRS ILRS IRS Isoleucine tRNA ligase isoleucyl tRNA synthetase PRO0785; IRS; isoleucine tRNA ligase 1, cytoplasmic; Isoleucine--tRNA ligase, cytoplasmic; Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, cytoplasmic
Cat # 16875265
150 µL
Cat # 16885265
20 µL
Cat # 16179117
100 µg
Cat # 16169117
50 µg
Cat # 15506422
100 µL
Cat # 16396714
100 µl
Cat # 16018007
100 uL
Cat # 16129744
100 µg
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