This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
CASP8 associated protein 2; CASP8-associated protein 2; CASP8AP2; FLASH homolog RIP25; FLICE associated huge; FLICE-associated huge protein; human FLASH
Cat # 16537941
100 µL
Cat # 11524660
100 µg
Cat # 11563381
100 µg
Cat # 12888162
100 µg
Cat # 11554650
100 µg
Cat # 11566902
100 µg
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