This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
ALOX5AP FLAP arachidonate 5-lipoxygenase-activating protein MK-886-binding protein five-lipoxygenase activating protein; Arachidonate 5-lipoxygenase-activating protein; FLAP; MK-886-binding protein
Cat # 11396553
100 µg
Cat # 16359884
100 µL
Cat # 15745327
0.1 mg
Cat # 16387064
100 µl
Cat # 16689524
100 µL
Cat # 11366253
100 µg
Cat # 17216813
100 µL
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