The mammalian Phospholipase Cg (PLCg) family has two closely related proteins, PLCg1 and PLCg2. The PLCg isozymes have the core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains and one SH3 domain. In response to extracellular stimuli, such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCg. Activated PLCg catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce the metabolic second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
fidgetin like 1 Fidgetin like protein 1 FIGNL1; fidgetin-like 1; Fidgetin-like protein 1
Cat # 16827544
150 µL
Cat # 15992305
100 µL
Cat # 15720922
100 µL
Cat # 16630295
100 µL
Cat # 16837544
20 µL
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