The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
FIG4 homolog, SAC domain containing lipid phosphatase; FIG4 homolog, SAC1 domain containing lipid phosphatase; FIG4 homolog, SAC1 lipid phosphatase domain containing; Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; Polyphosphoinositide phosphatase; RP1-249I4.1 ALS11 CMT4J KIAA0274 SAC3 dJ249I4.1 FIG4 homolog SAC domain containing lipid phosphatase FIG4 homolog SAC1 domain containing lipid phosphatase SAC domain-containing protein 3 Sac domain-containing inositol phosphatase 3 phosphatidylinositol 3 5-bisphosphate 5-phosphatase polyphosphoinositide phosphatase; Sac domain-containing inositol phosphatase 3; SAC domain-containing protein 3
Cat # 15969694
100 µL
Cat # 15863274
100 µL
Cat # 13219568
100 µL
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