EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLC-gamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.
EF hand domain containing 2; EF hand domain family, member D2; EF-hand domain family, member D2; EF-hand domain-containing protein D2; EFHD2 MGC4342 EF hand domain containing 2 EF-hand domain family member D2 RP3-467K16.3 SWS1 EF hand domain family member D2 swiprosin 1; swiprosin 1; Swiprosin-1; testicular tissue protein Li 62
Cat # 11346293
100 µg
Cat # 12879062
100 µg
Cat # 15759651
100 µL
Cat # 15744317
0.1 mg
Cat # 16020578
100 ug
Cat # 16899733
20 µL
Cat # 16013767
100 ug
Cat # 16547691
100 µL
Cat # 16307274
100 µl
Cat # 16889733
150 µL
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk To A Specialist NowIf an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.