This gene encodes a multifunctional protein that localizes both in the cytoplasm and in the nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage and plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants.
AIMP3 P18 ARS-interacting multifunctional protein 3 aminoacyl tRNA synthetase complex-interacting multifunctional protein 3 eukaryotic translation elongation factor 1 epsilon-1 multisynthase complex auxiliary component p18 p18 component of aminoacyl-tRNA synthetase; Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3; ARS-interacting multifunctional protein 3; Elongation factor p18; Eukaryotic translation elongation factor 1 epsilon-1; Multisynthase complex auxiliary component p18; p18 component of aminoacyl-tRNA synthetase complex
Cat # 15938834
100 µL
Cat # 15753641
100 µL
Cat # 16550522
100 µg
Cat # 16160856
50 µg
Cat # 13422397
100 µL
Cat # 15924384
400 µL
Cat # 16517821
100 µL
Cat # 16867433
150 µL
Cat # 16877433
20 µL
Cat # 16077997
100 uL
Cat # 17277593
100 µL
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