Transcription factor predomitly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5′-AGGTCA-3′ direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements ...
Cat # 15663715
100 µL
Cat # 15352361
50 µg
Cat # 13247918
100 µg
Cat # 13471287
100 µL
Cat # 15322361
50 µg
Cat # 16557791
100 µL
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