Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus. It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells. It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.
B-lymphocyte-induced maturation protein 1; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP-1; Positive regulatory domain I-binding factor 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PRDI-BF1; PRDI-binding factor-1; PRDM1 PR domain containing 1 with ZNF domain BLIMP1 MGC118922 MGC118923 MGC118924 MGC118925 PRDI-BF1 B-lymphocyte-induced maturation protein 1 OTTHUMP00000016918 PR-domain zinc finger protein 1 PRDI-binding factor-1 beta-interferon gene positive-regulatory domain I binding factor positive regulatory domain I-binding factor 1
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