BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.
56 kDa aspartic-like protease; asp 1; ASP1; Aspartic-like protease 56 kDa; Aspartyl protease 1; Beta-secretase 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; Beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; Down region aspartic protease; Down syndrome region aspartic protease; DRAP; memapsin 1; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase; transmembrane aspartic proteinase Asp1
Cat # 12838162
100 µg
Cat # 16069177
400 uL
Cat # 16031898
100 ug
Cat # 16029177
400 uL
Cat # 16835914
150 µL
Cat # 11506012
100 µg
Cat # 11564360
100 µg
Cat # 11559030
100 µg
Cat # 13454227
100 µL
Cat # 12858162
100 µg
Cat # 16845914
20 µL
Cat # 16135136
50 uL
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