B-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, maligt melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
94 kDa B-raf protein; B-Raf proto-oncogene serine/threonine-protein kinase (p94); murine sarcoma viral (v-raf) oncogene homolog B1; p94; Proto-oncogene B-Raf; Serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B; v-Raf murine sarcoma viral oncogene homolog B1
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100 µg
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100 µL
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25 ug
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100 µL
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400 µL
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0.1 mg
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100 µL
Cat # 10365220
400 µL
Cat # 15774456
0.1 ml
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100 µL
Cat # 16366254
100 µL
Cat # 15963934
100 µg
Cat # 11305473
100 µL
Cat # 10828860
400 µL
Cat # 16308904
100 µL
Cat # 13440066
100 ug
Cat # 17139545
100 µg
Cat # 15766214
25 ug
Cat # 16341805
100 µL
Cat # 11514971
100 µL
Cat # 16356364
100 µL
Cat # 15774446
0.1 ml
Cat # 11365293
100 µL
Cat # 13408164
100 ug
Cat # 16314475
100 µg
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