The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain
AARS2; alanine tRNA ligase 2, mitochondrial (putative); Alanine--tRNA ligase, mitochondrial; Alanyl-tRNA synthetase; alanyl-tRNA synthetase 2 mitochondrial putative AARSL COXPD8 KIAA1270 MT-ALARS MTALARS bA444E17.1 alaRS alanine tRNA ligase 2 mitochondrial putative alanine--tRNA ligase alanyl-tRNA synthetase like; alanyl-tRNA synthetase 2, mitochondrial (putative); alanyl-tRNA synthetase like; AlaRS; probable alanyl-tRNA synthetase, mitochondrial
Cat # 15775241
100 µL
Cat # 15939094
100 µL
Cat # 16005627
100 ug
Cat # 16822055
150 µL
Cat # 15664125
100 µL
Cat # 16832055
20 µL
Cat # 15524891
100 µg
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