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SMN-Exon7 Mouse anti-Human, Mouse, Clone: 3A8G11, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 60255-1-IG-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16887295

  • 121.38€ / 20 microlitros
Fecha estimada de envío: 01-06-2022
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Descripción

Descripción

This antibody, 60255-1-Ig, raised against the C-terminal region (275-294 aa) encoded by the exon 7.

The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.
Especificaciones

Especificaciones

SMN-Exon7
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P97801, Q16637
SMN1
SMN-Exon7 Fusion Protein Ag16615
20 μL
Primary
Mouse, Human
Liquid
Western Blot, Immunofluorescence, Immunocytochemistry
3A8G11
Unconjugated
SMN1
Component of gems 1, Gemin 1, SMN, SMN1, SMN2, SMNC, SMN-Exon7, SMNT, Survival motor neuron protein, T BCD541
Mouse
Protein G
RUO
20595, 6606
Antibody
IgG1
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Ofertas especiales