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ACROBiosystems Rhesus macaque Fc gamma RIII / CD16 Protein, His Tag

SPR & BLI verified

263.93€ - 2639.24€

Especificaciones

Número de acceso XP_014968661.2
Peso molecular 23.1 kDa
Fuente Rhesus macaque CD16, His Tag (FC6-R52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Gly 206 (Accession # A3RFZ7-1).
Inmunógeno Glu 21 - Gly 206
Requisitos de almacenamiento -20°C
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
17186301
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ACROBiosystems
FC6-R52H6-50UG
50 μg
263.93€
50 microgramos
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Fecha estimada de envío: 11-04-2024
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17176301
Ver documentos Detalles de la promoción
ACROBiosystems
FC6-R52H6-1MG
1 mg
2639.24€
1 miligramo
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Fecha estimada de envío: 11-04-2024
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Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.CD16a antigen is also known as Low affinity immunoglobulin gamma Fc region receptor III-A, Fc-gamma RIII-alpha. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placentaltrophoblasts.CD16a is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody­dependent cytotoxicity and clearance of immune complexes. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

XP_014968661.2
Rhesus macaque CD16, His Tag (FC6-R52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Gly 206 (Accession # A3RFZ7-1).
-20°C
Fc gamma RIII / CD16
Rhesus Macaque
PBS, pH7.4
HEK293
MABSol™ Fc Receptors
23.1 kDa
Glu 21 - Gly 206
FCGR3
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>90% as determined by SDS-PAGE
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