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![Invitrogen™ Human RET [A883F], GST Tag Recombinant Protein 10 μg](https://assets.fishersci.com/TFS-Assets/LSG/product-images/Cell_Bio_Rec_Prot_Invitrogen_Vial.jpg-650.jpg)
Invitrogen™ Human RET [A883F], GST Tag Recombinant Protein
This RET A883F Recombinant Human Protein (658-end) was expressed in insect cells.
Marca: Invitrogen™ A33506
Detalles adicionales : Peso : 0.01000kg
Descripción
- This RET A883F recombinant human protein (658–end) was expressed in insect cells
- RET receptor tyrosine kinase or RET proto-oncogene is a member of the cadherin superfamily, which are cell-surface receptors that transduce signals for cell growth and differentiation
- RET can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement
- Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia (type IIA), multiple endocrine neoplasia (type IIB), Hirschsprung disease, and medullary thyroid carcinoma
- RET signaling pathway plays a key role in the molecular mechanisms that orchestrate intestine organogenesis by regulating the development of both the nervous and lymphoid system in the gut
- RET A883F recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the Z’-LYTE™ assay
- Available in multiple pack sizes for convenient use
- Also available in our SelectScreen Kinase Profiling Service
Especificaciones
| NP_065681.1 | |
| 74.6 kDa | |
| RET Kinase Family | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Recombinant, Active, Cytoplasmic, Mutant |
| Kinase Assay | |
| 10 μg | |
| aa 658-end | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol | |
| Insect | |
| Liquid |