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Invitrogen™ PIP5K1C Recombinant Human Protein

This PIP5K1C Recombinant Human Protein (full length) was expressed in insect cells.

Marca:  Invitrogen™ A33579

Detalles adicionales : Peso : 0.00900kg

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Código de producto. 17188825

  • 2180.00€ / 100 microgramos
Fecha estimada de envío: 11-10-2022
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Descripción

Descripción

PIP5K1C lipid kinase or phosphatidylinositol-4-phosphate 5-kinase 1 gamma phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1C is found at synapses and has been found to play roles in endocytosis and cell migration. PIP5K1C directly associates with β-catenin and increases β-catenin activity downstream of growth factor stimulation. PIP5K1C expression and kinase activity enhance β-catenin phosphorylation on residues that promote nuclear importation and transcriptional activity. PIP5K1C deficiency impairs neutrophil recruitment as a result of defect in adhesion. PIP5K1C regulated the adhesion through facilitation of RhoA GTPase and integrin activation by chemoattractants.
  • Validated for use with the Adapta™ assay
  • Available in multiple pack sizes for convenient use
Especificaciones

Especificaciones

NP_036530.1
100 µg
Full Length
GST Tag
Dry Ice
Kinases & Inhibitors
Liquid
Human
99.6 kDa
PI3 Kinase
Yes
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol
Baculovirus
Full Length, Recombinant, Active
Kinase Assay
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales