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STEMCELL Technologies Pifithrin-mu
p53 inhibitor
Marca: STEMCELL Technologies 72802
Detalles adicionales : Peso : 0.05000kg
Descripción
- Pifithrin-mu (PFT-μ) is an inhibitor of p53-mediated apoptosis, preventing p53 binding to Bcl-xL and Bcl-2 at the mitochondrial surface, without affecting p53 transactivational activities (Strom et al.) In vitro, PFT-μ binds both p53 (Kd = 0.82 mM) and Bcl-xL (Kd = 0.80 mM; Hagn et al.)
- In combination with Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor Y-27632, improves cell recovery after cryopreservation (Xu et al.)
- Inhibits DNA damage-induced apoptosis in human embryonic stem cells (Qin et al.)
Especificaciones
64984-31-2 | |
10 mg | |
≥98% |
2-Phenylethynesulfonamide; PFT-μ; Pifithrin-μ | |
C8H7NO2S |