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OBFC2B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 14809-1-AP-20UL
Detalles adicionales : Peso : 0.00010kg
Descripción
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintece of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.Especificaciones
OBFC2B | |
Polyclonal | |
Unconjugated | |
NABP2 | |
hSSB1, OBFC2B, Sensor of ssDNA subunit B1, SOSS B1, SOSS complex subunit B1, SSB1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
362813, 69917, 79035 | |
-20°C | |
Liquid |
Immunocytochemistry, Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence | |
0.3 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q3SWT1, Q8R2Y9, Q9BQ15 | |
Nabp2 | |
OBFC2B Fusion Protein Ag6532 | |
20 μL | |
Primary | |
Mouse, Rat, Human | |
Antibody | |
IgG |