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Nestin Mouse, anti-Human, Unconjugated, Clone: 10C2, STEMCELL Technologies

Mouse Monoclonal Antibody

Marca:  Stemcell Technologies 60091

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17188961

  • 420.28€ / 100 microgramos
Fecha estimada de envío: 11-11-2022
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Descripción

Descripción

  • The 10C2 antibody reacts with human nestin, a class VI intermediate filament (IF) protein expressed by embryonic neuroepithelial stem cells in the developing nervous system and by pancreatic islet and mesenchymal progenitor cells
  • Nestin expression is also observed in glioblastomas and many primary and metastatic melanomas and it is a useful angiogenic marker to evaluate neovascularity of endothelial cells in tumors
  • Nestin is required for the survival and renewal of neural progenitor cells and plays roles in cellular remodeling by forming heterodimers with vimentin or alpha-internexin, a process that appears to be tightly regulated by phosphorylation
  • Nestin localizes to the growth cones during axon elongation in differentiating neurons and may play a role in growth cone guidance
  • Nestin expression is down-regulated during differentiation, typically disappearing by embryonic stage E18
  • The 10C2 antibody reportedly cross-reacts weakly with monkey nestin but not rodent nestin
Especificaciones

Especificaciones

Nestin
Monoclonal
Unconjugated
100 μg
Human, Cynomolgus
Neural Cells, PSC-Derived, Neural Stem and Progenitor Cells, Neurons
Immunofluorescence, Immunocytochemistry, Flow Cytometry, Western Blot, Immunohistochemistry
10C2
Mouse
Primary
IgG1 κ
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales