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ACROBiosystems Mouse CD79B Protein, Fc Tag

Marca:  ACROBiosystems CDB-M5253-100ug

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 17206140

  • 399.17€ / 100 microgramos
Fecha estimada de envío: 24-10-2022
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Descripción

Descripción

B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.3 kDa.
Especificaciones

Especificaciones

Powder
100 μg
Val 26 - Asp 158
CD79b,B29,IGB,Ig-beta
Unconjugated
HEK293
Mouse
40.3 kDa
Mouse CD79B, Fc Tag (CDB-M5253) is expressed from human 293 cells (HEK293). It contains AA Val 26 - Asp 158 (Accession # P15530-1).
-20°C
CD79B
Fc Tag
Bio-Markers & CD Antigens
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