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MAP3K10 (MLK2) Recombinant Human Protein
MAP3K10 (MLK2) Recombinant Human Protein
Marca: Invitrogen PV3877
Detalles adicionales : Peso : 0.05250kg
Descripción
MAP3K10 (MLK2) is a serine⁄threonine kinase which has been shown to activate MAPK8⁄JNK and MKK4⁄SEK1. This kinase itself can be phoshorylated, and is thus activated by JNK kinases. MAP3K10 functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.Especificaciones
| NP_002437 | |
| Cell Viability, Pharma and Biopharma, Cell Proliferation and Function, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| 131.2kDa | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| MAP3K10 (MLK2) | |
| MAP3K10 (MLK2) was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100μM ATP, 450μg/mL myelin basic protein (MBP) and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| MAP3K10 (MLK2) Recombinant Human Protein | |
| Human | |
| Baculovirus | |
| Serine/threonine kinase |
| 0.34mg/mL | |
| 114294, 4294 | |
| MAP3K10 (MLK2) Recombinant Human Protein | |
| –80°C | |
| 1 Each | |
| MAP3K10 (MLK2) Recombinant Human Protein | |
| MLK | |
| 59nmoles of phosphate transferred to myelin basic protein (MBP) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL | |
| GST Tag | |
| Kinase and inhibitors | |
| 60% by SDS-PAGE |
For Research Use Only. Not for use in diagnostic procedures.