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MMP-2 (72kDa Collagenase IV) Ab-1 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in experiments with the Epredia™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody.
Marca: Epredia MS-567-P1ABX
Detalles adicionales : Peso : 1.00000kg
Descripción
MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids into an active form.of 62kDa.Host Species: Mouse
Clone: CA-4001 or CA719E3C
Isotype: IgG1
Species Reactivity: Human, Mouse and Rat. Others not known.
Epitope: N-terminal (APSPIIKFPGD-VAPKTDK)
Immunogen: N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV
Molecular Weight: 72kDa (proform)
Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells
Cellular Localization: Cytoplasmic
Recommended for:
- Western Blotting
- Immunoprecipitation (Not suitable)
- Inhibition of MMP-2 Activity
Note:
USA: RUO; Int'l: RUO
Especificaciones
| MMP-2 (72kDa Collagenase IV) Ab-1 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 100 μL | |
| Proteases And Inhibitors | |
| Human, Mouse, Rat | |
| IgG1 |
| Western Blot | |
| CA-4001 or CA719E3C | |
| Unconjugated | |
| N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV | |
| RUO | |
| Primary | |
| Concentrated |