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Epredia™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-13 Mouse Monoclonal Antibody
Obtain accurate, reproducible results in immunoprecipitation experiments with Epredia™ Epidermal Growth Factor Receptor/EGFR Ab-13, Mouse Monoclonal Antibody.
Marca: Epredia™ MS-609-B
Detalles adicionales : Peso : 1.00000kg
Descripción
EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Host Species: Mouse
Clone: 528 + 199.12
Isotype: IgG2a + IgG2a
Species Reactivity: Human. Does not react with mouse and rat. Others not known.
Epitope: Extracellular domain
Immunogen: Partially purified EGFR from A431 cells (clone 528) and extracellular domain of recombinant human EGFR protein (clone 199.12)
Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)
Positive Control: A431 cells
Cellular Localization: Membrane
Recommended for:
- Immunoprecipitation (Native and denatured)
Note:
USA: RUO; Int'l: RUO
Especificaciones
| Epidermal Growth Factor Receptor/EGFR Ab-13 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| A431 cells | |
| RUO | |
| Primary | |
| Concentrated |
| Immunoprecipitation | |
| 528 + 199.12 | |
| Biotin | |
| Partially purified EGFR from A431 cells (clone 528) and extracellular domain of recombinant human EGFR protein (clone 199.12) | |
| 1 mL | |
| EGFR Family | |
| Human | |
| IgG2a |