Epredia™ Lab Vision™ Calponin Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Descripción

Calponin, a calmodulin, binds tropomyosin and F-actin and is thought to be involved in the regulation of smooth muscle contraction. The expression of calponin is restricted to smooth muscle cells and is a marker of the differentiated contractile phenotype of developing smooth muscle. Two isoforms of calponin exist whose molecular weights are 34 kDa and 29 kDa. Expression of the 29 kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions.

Host Species: Mouse

Clone: CALP

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not tested.

Epitope: Not determined

Immunogen: Crude human uterus extract

Molecular Weight: 34 kDa

Positive Control: Myoepithelial cells in breast ducts

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)