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ACROBiosystems Human PSGL-1 / CD162 Protein, His Tag

Marca:  ACROBiosystems PS1-H52H9-100ug

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 17186631

  • 399.17€ / 100 microgramos
Fecha estimada de envío: 14-10-2022
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Descripción

Descripción

P-selectin glycoprotein ligand 1 (PSGL-1) is also known as Selectin P ligand (SELPLG), CD antigen CD162. PSGL-1 is disulfide-linked homodimer which is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 / SELPLG interacts with P-, E- and L-selectins, through their lectin/EGF domains, is required for promoting recruitment and rolling of leukocytes. These interactions require sialyl Lewis X glycan modification but there is a differing dependence for tyrosine sulfations. Dimerization appears not to be required for P-selectin/SELP binding. PSGL-1 can interact with SNX20, MSN and SYK. PSGL-1 / SELPLG mediate the activation of SYK by SELPLG.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30.7 kDa. The protein migrates as 55-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_002997.2
30.7 kDa
100 µg
Gln 42 - Cys 320
PSGL1,CD162,SELPLG,Selectin P ligand
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Human PSGL-1, His Tag (PS1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 42 - Cys 320 (Accession # Q14242-1).
-20°C
PSGL-1
His Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
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Ofertas especiales

Ofertas especiales