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ACROBiosystems Human IL-2 R beta&IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag

MALS verified

Marca:  ACROBiosystems ILG-H5254-1mg

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 17196441

  • 2896.79€ / 1 miligramo
Fecha estimada de envío: 20-10-2022
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Descripción

Descripción

Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Human IL-2RB&IL-2RG Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of IL-2RB and IL-2RG, has a calculated MW of 51.1 kDa (IL-2RB) and 53.6 kDa (IL-2RG). Subunit IL-2RB is fused with a human IgG1 Fc tag at the C-terminus and subunit IL-2RG
Especificaciones

Especificaciones

NP_000869.1 (IL-2 RB) and AAH14972.1 (IL-2 RG)
51.1 kDa (IL-2 RB) and 53.6 kDa (IL-2 RG)
1 mg
Ala 27 - Asp 239 (IL-2 RB) and Leu 23 - Asn 254 (IL-2 RG)
IL-2 R beta and IL-2 R gamma,IL-2 RB and IL-2 RG
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human IL-2 RB&IL-2; RG Heterodimer Protein, Fc Tag&Fc; Tag (MALS verified) (ILG-H5254) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Asp 239 (IL-2 RB) and Leu 23 - Asn 254 (IL-2 RG) (Accession # P14784-1 (IL-2 RB) and P31785-1 (IL-2 RG)).
-20°C
IL-2 R beta and IL-2 R gamma
Fc Tag
Less than 1.0 EU / µg by the LAL method.
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