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ACROBiosystems Human IL-2 R beta / CD122 Protein, His Tag

SPR verified

Marca:  ACROBiosystems CD2-H5221-500UG

Detalles adicionales : Peso : 0.00001kg

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Código de producto. 15886147

  • 2135.39€ / 500 microgramos
Fecha estimada de envío: 20-02-2023
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Descripción

Descripción

Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.4 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_000869.1
25.4 kDa
500 µg
Ala 27 - Asp 239
IL2RB,RP5-1170K4.6,CD122,P70-75
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Human IL-2 R beta, His Tag (SPR verified) (CD2-H5221) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Asp 239 (Accession # NP_000869.1).
-20°C
IL-2 R beta
His Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
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