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ACROBiosystems Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free

MALS verified

Marca:  ACROBiosystems CDA-H52W5-1mg

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 17186181

  • 3512.64€ / 1 miligramo
Fecha estimada de envío: 18-10-2022
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Descripción

Descripción

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.

Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free, produced by co-expression of CD8 alpha and CD8 beta, has a calculated MW of 19.5 kDa (CD8 alpha) and 22.1 kDa (CD8 beta). Subunit CD8 alpha is fused with a polyhistidine tag at the C-terminus and subu
Especificaciones

Especificaciones

NP_001759.3 (CD8A)/NP_004922.1 (CD8B)
19.5 kDa (CD8A) and 22.1 kDa (CD8B)
1 mg
Ser 22 - Asp 182 (CD8A) and Leu 22 - Pro 170 (CD8B)
CD8 alpha and beta,CD8A and CD8B
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human CD8A&CD8B; Heterodimer Protein, His Tag&Tag; Free (CDA-H52W5) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Asp 182 (CD8A) and Leu 22 - Pro 170 (CD8B) (Accession # P01732-1 (CD8A) and P10966-1 (CD8B)).
-20°C
CD8 alpha and beta
His Tag
Less than 1.0 EU / µg by the LAL method.
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