missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Human CD40 / TNFRSF5 Protein, Mouse IgG2a Fc Tag, low endotoxin

MALS verified

Marca:  ACROBiosystems CD0-H525A-1MG

Detalles adicionales : Peso : 0.00001kg

 Ver más versiones de este producto

Código de producto. 15896127

  • 2651.24€ / 1 miligramo
Fecha estimada de envío: 20-02-2023
para ver el stock

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.


Descripción

Descripción

CD40 is also known as TNFRSF5, Bp50, CDW40, MGC9013, TNFRSF5 and p50, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins, and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 contains 4 cysteine-rich repeats in the extracellular domain, and is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines.

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 46.1 kDa. The protein migrates as 58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_001241.1
46.1 kDa
1 mg
Glu 21 - Arg 193
CD40,Bp50,CDW40,MGC9013,TNFRSF5,p50
Unconjugated
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human CD40, Mouse IgG2a Fc Tag, low endotoxin (MALS verified) (CD0-H525a) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Arg 193 (Accession # P25942-1).
-20°C
CD40
Mouse IgG Fc Tag
Less than 0.1 EU / µg by the LAL method.
Immune Checkpoint Proteins
Videos
SDS
Documentos

Documentos

Certificados
Ofertas especiales

Ofertas especiales