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ACROBiosystems Human CD40 / TNFRSF5 Protein, Mouse IgG2a Fc Tag, low endotoxin

MALS verified

359.89€ - 2639.24€

Especificaciones

Número de acceso NP_001241.1
Peso molecular 46.1 kDa
Fuente Human CD40, Mouse IgG2a Fc Tag, low endotoxin (MALS verified) (CD0-H525a) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Arg 193 (Accession # P25942-1).
Inmunógeno Glu 21 - Arg 193
Requisitos de almacenamiento -20°C
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15896127
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ACROBiosystems
CD0-H525A-1MG
1 mg
2639.24€
1 miligramo
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Fecha estimada de envío: 11-04-2024
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15886127
Ver documentos Detalles de la promoción
ACROBiosystems
CD0-H525A-100UG
100 μg
359.89€
100 microgramos
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»
Fecha estimada de envío: 11-04-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

CD40 is also known as TNFRSF5, Bp50, CDW40, MGC9013, TNFRSF5 and p50, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins, and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 contains 4 cysteine-rich repeats in the extracellular domain, and is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines.

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 46.1 kDa. The protein migrates as 58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_001241.1
Human CD40, Mouse IgG2a Fc Tag, low endotoxin (MALS verified) (CD0-H525a) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Arg 193 (Accession # P25942-1).
-20°C
CD40
Human
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
46.1 kDa
Glu 21 - Arg 193
CD40,Bp50,CDW40,MGC9013,TNFRSF5,p50
Unconjugated
Mouse IgG Fc Tag
Less than 0.1 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
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SDS
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