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ACROBiosystems Cynomolgus TSLP Protein, His Tag
Marca: ACROBiosystems TSP-C52H8-100ug
Detalles adicionales : Peso : 0.00010kg
Descripción
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.
This protein carries a polyhistidine tag at the C-terminus. This protein contains a furin convertase cleavage site, 127-RRKR-130, and will be processed into N and C-terminal fragment with calculated MW of 11.7 kDa and 5.4 kDa respectively. The protein migEspecificaciones
| XP_005557555.1 | |
| 100 μg | |
| Tyr 29 - Gln 159 | |
| TSLP | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 11.7 kDa and 5.4 kDa | |
| Cynomolgus TSLP, His Tag (TSP-C52H8) is expressed from human 293 cells (HEK293). It contains AA Tyr 29 - Gln 159 (Accession # A0A2K5TXV0-1). | |
| -20°C | |
| TSLP | |
| Cynomolgus Monkey | |
| PBS, pH7.4 | |
| HEK293 | |
| Other Recombinant Proteins |