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CD8a Rat, anti-Mouse, FITC, Clone: 53-6.7, STEMCELL Technologies

Rat Monoclonal Antibody

Marca:  Stemcell Technologies 60023FI.1

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17198551

  • 98.42€ / 50 microgramos
Fecha estimada de envío: 16-12-2022
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Descripción

Descripción

  • The 53-6.7 antibody reacts with murine CD8a, a 32 - 34 kDa type I transmembrane glycoprotein which is a subunit of CD8
  • CD8 is a disulfide-bonded dimer, found either as a heterodimer of CD8a (α) and CD8b (β) subunits (i.e., αβ) or a homodimer (αα)
  • CD8 acts as a co-receptor to the T cell receptor (TCR) during T cell activation by binding MHC Class I molecules presented by an antigen-presenting cell
  • It functions to strengthen the association between the TCR and MHC I-antigen complex and to amplify signals from the TCR to the cytoplasm through the interaction of its intracellular domain with cytoplasmic tyrosine kinases such as Lck
  • The CD8a chain binds to the alpha-3 domain of class I MHC molecules
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD8+ T Cell Isolation Kit (Catalog #19853) and EasySep™ Mouse CD90.2 Positive Selection Kit II (Catalog #18951)
Especificaciones

Especificaciones

CD8a
Monoclonal
FITC
50 μg
Frog, Mouse
T Cells, T Cells, CD8+
Functional Assay, Immunofluorescence, Immunocytochemistry, Flow Cytometry, CyTOF
53-6.7
Rat
Primary
IgG2a κ
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