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CD7 Recombinant Rabbit Monoclonal Antibody (15), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Marca: Invitrogen MA543531
Detalles adicionales : Peso : 0.01000kg
Descripción
Specificity: Human CD7/LEU9
CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.Especificaciones
CD7 | |
Recombinant Monoclonal | |
1 mg/mL | |
PBS with no preservative | |
P09564 | |
CD7 | |
Recombinant Human CD7 protein. | |
50 μL | |
Primary | |
Human | |
Antibody | |
IgG |
ELISA, Immunohistochemistry (Paraffin) | |
15 | |
Unconjugated | |
CD7 | |
Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41 | |
Rabbit | |
Protein A | |
RUO | |
924 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |