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CD19 Rat, anti-Mouse, Alexa Fluor 488, Clone: 6D5, STEMCELL Technologies

Rat Monoclonal Antibody

Marca:  Stemcell Technologies 60006AD

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17198361

  • 385.70€ / 100 microgramos
Fecha estimada de envío: 08-11-2022
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Descripción

Descripción

  • The 6D5 antibody reacts with CD19, an ∼95 kDa type 1 transmembrane glycoprotein expressed on the surface of B cells throughout all stages of development, from early pre-B cells to plasma cells
  • Expression is down-regulated but persists in terminally differentiated plasma cells
  • CD19 is also found on follicular dendritic cells
  • By associating with CD21 and CD81, CD19 functions as a co-receptor for the B cell receptor and is involved in B cell activation and differentiation
  • Activation of CD19 is accompanied by phosphorylation of the cytoplasmic domain, which promotes binding to kinases and the induction of intracellular signaling cascades
  • Mutations in CD19 can result in severe immunodeficiency syndromes
  • Clone 6D5 recognizes the same epitope as clone ID3 in cross-competition assays
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse B Cell Isolation Kit (Catalog #19854)
Especificaciones

Especificaciones

CD19
Monoclonal
Alexa Fluor 488
100 μg
Mouse
B Cells
Immunofluorescence, Immunocytochemistry, Flow Cytometry, Western Blot, Immunohistochemistry
6D5
Rat
Primary
IgG2a κ
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Ofertas especiales

Ofertas especiales