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ACROBiosystems Biotinylated Human Syndecan-1 Protein, His, Avitag™

Biotinylated Protein

Marca:  ACROBiosystems SY1-H82E2-25ug

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 17196781

  • 399.17€ / 25 microgramos
Fecha estimada de envío: 25-10-2022
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Descripción

Descripción

Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 27.5 kDa. The protein migrates as 43-55 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
Especificaciones

Especificaciones

Powder
>90% as determined by SDS-PAGE
Biotinylated Human Syndecan-1, His,Avitag™ (SY1-H82E2) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 254 (Accession # P18827-1).
-20°C
Syndecan-1
His Tag and Avi Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
27.5 kDa
25 µg
Gln 23 - Gly 254
SDC1,Syndecan-1,CD138,SYND1,SDC
Precision Avi
PBS, pH7.4
HEK293
Human
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SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales