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ACROBiosystems Biotinylated Human IL-13 Protein, His, Avitag™

Biotinylated Protein

Marca:  ACROBiosystems IL3-H82E5-200ug

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16477699

  • 1542.32€ / 200 microgramos
Fecha estimada de envío: 04-08-2022
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Descripción

Descripción

Interleukin 13 (IL13) is also known as ALRH, BHR1and P600, is a single-chain glycosylated polypeptide, and is a cytokine critical in regulating inflammatory and immune responses. IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. IL-13 induces matrix metalloproteinases (MMPs) as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 15.9 kDa. The protein migrates as 17 kDa and 28-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_002179.2
15.9 kDa
200 µg
Gly 21 - Asn 132
IL13,ALRH,BHR1,MGC116786,MGC116788,MGC116789,P600,Interleukin-13
Precision Avi
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Biotinylated Human IL-13, His,Avitag (IL3-H82E5) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Asn 132 (Accession # AAK53823.1).
-20°C
IL-13
His Tag and Avi Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
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