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![AXL [R499C] Recombinant Human Protein, Invitrogen™ 10μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
AXL [R499C] Recombinant Human Protein, Invitrogen™
AXL is a transforming gene isolated from primary human myeloid leukemia cells. Recombinant human AXL R499C (473-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Marca: Invitrogen PV6253
Detalles adicionales : Peso : 0.01000kg
Descripción
AXL encodes a novel receptor tyrosine kinase which is a member of the TAM (TYRO3/AXL/MER) receptor tyrosine kinase subfamily. AXL represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats and Axl transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. AXL is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Especificaciones
| Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation | |
| 73.5kDa | |
| Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. | |
| aa 473-end | |
| Recombinant |
| 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol | |
| 10μg | |
| UFO, JTK11 | |
| Human | |
| GST Tag |