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Cyclin E Mouse anti-Human, Unlabeled, Clone: HE12, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 551160

Detalles adicionales : Peso : 0.02000kg

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Código de producto. 15876558

  • 554.04€ / cada uno
Fecha estimada de envío: 17-02-2023
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Descripción

Descripción

Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes. Cyclins (regulatory subunits) bind to cdks (catalytic subunits) to form complexes that regulate the progression of the cell cycle. These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small proteins that bind to cyclins, cdks, or cyclin-cdk complexes, e.g., p21 and p27 [Kip1]. Cyclin E is expressed in G1 and associates with cdk2 to form an active kinase where it plays an important role in the regulation of the G1/S restriction checkpoint in the cell cycle. Abberant expression of cyclin E has been reported to be associated with the oncogenic transformation of cells. This antibody has been reported not to cross-react with mouse cyclin E.

Especificaciones

Especificaciones

Cyclin E
Monoclonal
Unconjugated
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Western Blot
HE12
Mouse
150 μg
Cell Biology
Human
IgG1
Videos
SDS
Documentos

Documentos

Certificados
Ofertas especiales

Ofertas especiales

For Research Use Only.