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AHNAK Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 16637-1-AP-20UL
Detalles adicionales : Peso : 0.00010kg
Descripción
AHNAK1 (Desmoyokin) is a large (700 kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels. AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation. In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane, connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture. In epithelial cells, AHNAK1 is localized in cytoplasm or is membrane-associated, but in cells of nonepithelial origin AHNAK1 is predomitly nuclear; it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex.Especificaciones
AHNAK | |
Polyclonal | |
Unconjugated | |
AHNAK | |
AHNAK, AHNAK nucleoprotein, AHNAKRS, Desmoyokin, PM227 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
79026 | |
-20°C | |
Liquid |
Flow Cytometry, Western Blot, Immunofluorescence, Immunocytochemistry | |
0.6 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q09666 | |
AHNAK | |
AHNAK Fusion Protein Ag9986 | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |