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WASP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 10987-1-AP-150UL

Detalles adicionales : Peso : 0.00010kg

 Ver más versiones de este producto

Código de producto. 16817743

  • 319.00€ / 150 microlitros

Envío estimado: 21-10-2021

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Descripción

Descripción

The Wiskott-Aldrich syndrome family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5′ UTR sequence, has been described, however, its full-length nature is not known.
Especificaciones

Especificaciones

WASP
0.29 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P42768, P70315
IMD2, THC, THC1, WAS, WASP
Rabbit
IgG
150 μL
-20°C
Primary
22376, 317371, 7454
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
WAS
Liquid
Was
WASP Fusion Protein Ag1444
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Videos
SDS
Documentos
Certificados