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TRAC-1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA590268
Detalles adicionales : Peso : 0.01000kg
Descripción
Immunogen sequence: MGSVLSTDSG KSAPASATAR ALERRRDPEL PVTSFDCAVC LEVLHQPVRT RCGHVFCRSC IATSLKNNKW TCPYCRAYLP SEGVPATDVA KRMKSEYKNC AECDT; Positive Samples: Raji, K-562
TRAC-1 is a 232 amino acid protein containing an N-terminal RING-type zinc finger domain. It functions as a positive regulator in the T-cell receptor signaling pathway, thus leading to T-cell activation. It mediates ubiquitination and subsequent proteasomal degradation of target proteins. TRAC-1 is expressed in lymphoid tissues, including bone marrow, spleen, thymus as well as in other tissues. It is predominantly expressed in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells.Especificaciones
| TRAC-1 | |
| Polyclonal | |
| Unconjugated | |
| RNF125 | |
| 4930553F04Rik, E3 ubiquitin-protein ligase RNF125, RING finger protein 125, ring finger protein 125, E3 ubiquitin protein ligase, RNF125, T-cell RING activation protein 1, T-cell ring protein identified in activation screen, TNORS, TRAC1, TRAC-1 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 54941 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 2.08 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal, pH 7.3 | |
| Q96EQ8 | |
| RNF125 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human RNF125 (NP_0603012) | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |