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TDP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 10641-1-AP-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16887143

  • 325.38€ / 150 microlitros
Fecha estimada de envío: 25-05-2022
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Descripción

Descripción

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.
Especificaciones

Especificaciones

TDP1
Polyclonal
Unconjugated
TDP1
TDP1, Tyr DNA phosphodiesterase 1
Rabbit
Antigen Affinity Chromatography
RUO
104884, 314380, 55775
Antibody
IgG
Immunoprecipitation, Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q4G056, Q8BJ37, Q9NUW8
Tdp1
TDP1 Fusion Protein Ag0964
150 μL
Primary
Human, Mouse, Rat
Liquid
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Ofertas especiales

Ofertas especiales