Applied Biosystems™ TaqMan™ Array Human Alzheimer's Disease

Descripción

The panel of assays in this plate is based on the amyloid hypothesis. The 92 genes are involved in APP processes that generate beta-amyloid and included genes implicated in multiple secondary steps of beta-amyloid aggregation, tau hyperphosphorylation, excitotoxicity, inflammation, oxidation and microglial activation. We also include assays for genes involved in cholesterol biosynthesis due to the correlation between high cholesterol and increased risk of Alzheimer's. Genes associated with Alzheimer's disease pathology, biochemistry and genetics are also included. Gene Signature Plates are 96-well plates that are pre-configured with the most appropriate TaqMan Gene Expression Assays for a specific biological process, pathway, or disease state. Each plate contains predefined assays and endogenous controls dried-down in the wells, ready for accurate assessment of an entire gene signature in one simple experiment.

TaqMan Array Plates contain the same TaqMan Gene Expression Assays that have been available for years in a convenient, 96-well format. Extensive tests have found no difference in performance between TaqMan Assays supplied in the traditional format and assays dried into a TaqMan Array Plate.

Each pack of plates is shipped with a CD containing the plate map along with details of each assay. This information is imported into the real-time PCR instrument to enable proper labeling of data and access to Assay ID numbers for simple reordering.

• Asequible; pedido mínimo de tres placas; ideal para proyectos pequeños, medianos o grandes.
• Entrega rápida; en su laboratorio en cuestión de días.
• Prácticos; los juegos de sondas TaqMan™ y cebador para PCR seca se suministran en una placa de 96 pocillos; solo tiene que añadir la mezcla maestra y la muestra
• Las placas de matriz TaqMan se han optimizado para su uso con la mezcla maestra de expresión génica TaqMan, pero también son compatibles con la mezcla maestra de PCR universal TaqMan.
• Para los estudios que utilizan células cultivadas, las placas de matriz TaqMan también son compatibles (y recomendadas) con el kit TaqMan Gene Expression Cells-to-Ct™.
• Las placas de matriz TaqMan™ deben procesarse en un instrumento de PCR en tiempo real con capacidad de placa de 96 pocillos
• Las placas se han validado para su uso en sistemas de PCR en tiempo real Applied Biosystems™ 7000, 7300, 7500 y 7900HT Fast con bloques de 96 pocillos estándar, condiciones de ciclos de PCR estándar y reacción de 20 μl.