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SMTN Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 23567-1-AP-20UL
Detalles adicionales : Peso : 0.00010kg
Descripción
Smoothelin is a constituent of the smooth muscle cell (SMC) cytoskeleton. Antibodies directed to smoothelin are a useful tool to monitor SMC differentiation. Smoothelin is exclusively expressed in fully differentiated (contractile) SMCs. RNA and protein analyses reveal a broad species distribution of this protein. Cells with SMC-like characteristics, such as myofibroblasts, myoepithelial cells, and skeletal and cardiac muscle do not contain smoothelin. Confocal scanning laser microscopy of tissue sections, as well as transfection studies, show a filamentous organization of smoothelin that is different from that of desmin and vimentin. Smoothelin colocalizes with actin stress fibers. Two tissue specific isoforms have been identified: a 59 kDa isoform specific for visceral SMC; and a 100 kDa specific for vascular SMC. Human smoothelin is encoded by a single copy gene which is located on chromosome 22.Especificaciones
SMTN | |
Polyclonal | |
Unconjugated | |
SMTN | |
smoothelin, SMSMO, SMTN | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
29856, 6525 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.33 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P53814, Q921U8 | |
SMTN | |
SMTN Fusion Protein Ag19983 | |
20 μL | |
Primary | |
Mouse, Human | |
Antibody | |
IgG |